Indeed, the new intimate dating between pain and you will oxidative damage are better-understood within the literature ( Cesari et al 2005 )
The human being telomerase contrary transcriptase (hTERT), the latest ingredient of telomerase, might have been identified and you can cloned and its particular messenger RNA try hidden in the classified muscle that don’t express telomerase, but is loaded in undifferentiated tissues declaring telomerase ( Meyerson ainsi que al 1997 ). Regardless of if post-transcriptional mechanisms may tailor hTERT hobby ( Liu ainsi que al 1999 ), the term out of hTERT correlates really which have telomerase craft and you may large research reveals that hTERT pastime was controlled mostly on peak of transcription ( Cong ainsi que al 1999 ; Wick mais aussi al 1999 ). (περισσότερα…)